Applicaiton Required

ISPY1

ACRIN 6657 was designed as a prospective study to test MRI for ability to predict response to treatment and risk-of-recurrence in patients with stage 2 or 3 breast cancer receiving neoadjuvant chemotherapy (NACT). ACRIN 6657 was conducted as a companion study to CALGB 150007, a correlative science study evaluating tissue-based biomarkers in the setting of neoadjuvant treatment of breast cancer. Collectively, CALGB 150007 and ACRIN 6657 formed the basis of the multicenter Investigation of Serial Studies to Predict Your Therapeutic Response with Imaging and moLecular Analysis (I-SPY TRIAL) breast cancer trial, a study of imaging and tissue-based biomarkers for predicting pathologic complete response (pCR) and recurrence-free survival (RFS).Participant Eligibility and Enrollment: Criteria for inclusion were patients enrolling on CALGB 150007 with T3 tumors measuring at least 3 cm in diameter by clinical exam or imaging and receiving neoadjuvant chemotherapy with an anthracycline-cyclophosphamide regimen alone or followed by a taxane. Pregnant patients and those with ferromagnetic prostheses were excluded from the study. The study was open to enrollment from May 2002 to March 2006. 237 patients were enrolled, of which 230 met eligibility criteria.

Acknowledgements This shared data set was provided by David Newitt, PhD and Nola Hylton, PhD from the Breast Imaging Research Program at UCSF, in collaboration with ACRIN, CALGB, the I-SPY TRIAL, and TCIA. Many thanks are due to The ACRIN 6657 trial team, The I-SPY 1 TRIAL team, and all the patients participating in these studies

Funding sources include NIH grants to UCSF (R01 CA132870 and U01 CA151235), ACRIN (UO1 CA079778 and UO1 CA080098), and CALGB (UO1 CA31964 and UO1 CA33601).

Data and Resources

This dataset has no data

Additional Info

Field Value
Last Updated December 3, 2019, 14:29 (CST)
Created February 14, 2019, 10:19 (CST)

推薦資料集:


  • 廢(污)水產生量及排放量

    Payment instrument Free
    Update frequency Irregular
    本資料依全國及縣市別統計廢(污)水產生量及排放量,並依來源分類。
  • 高雄市大寮區107年公告地價

    Payment instrument Free
    Update frequency Irregular
    107年-高雄市大寮區公告地價
  • 綜合所得稅各類所得件數各級距申報統計表-縣市別:高雄市

    Payment instrument Free
    Update frequency Irregular
    綜合所得稅各類所得件數各級距申報統計表-縣市別:高雄市 單位:件數
  • 新北市政府福利補助資訊

    Payment instrument Free
    Update frequency Irregular
    新北市福利補助資訊,提供各種補助資訊,包括補助說明及申請方式。
  • 臺南市焚化廠地址

    Payment instrument Free
    Update frequency Irregular
    本資料集提供臺南市焚化廠地址資訊。