Applicaiton Required

RIDER NEURO MRI

RIDER Neuro MRI contains imaging data on 19 patients with recurrent glioblastoma who underwent repeat imaging sets. These images were obtained approximately 2 days apart (with the exception of one patient, RIDER Neuro MRI-1086100996, whose images were obtained one day apart).
DCE‐MRI: All 19 patients had repeat dynamic contrast‐enhanced MRI (DCE‐MRI) datasets on the same 1.5T imaging magnet. On the basis of T2‐weighted images, technologists chose 16 image locations using 5mm thick contiguous slices for the imaging. For T1 mapping, multi‐flip 3D FLASH images were obtained using flip angles of 5, 10, 15, 20, 25 and 30 degrees, TR of 4.43 ms, TE of 2.1 ms, 2 signal averages. Dynamic images were obtained during the intravenous injection of 0.1mmol/kg of Magnevist intravenous at 3ccs/second, started 24 seconds after the scan had begun. The dynamic images were acquired using a 3D FLASH technique, using a flip angle of 25 degrees, TR of 3.8 ms, TE of 1.8 ms using a 1 x1 x 5mm voxel size. The 16 slice imaging set was obtained every 4.8 sec.

DTI: Seventeen of the 19 patients also obtained repeat diffusion tensor imaging (DTI) sets. Whole brain DTI were obtained using TR 6000ms, TE 100 ms, 90 degree flip angle, 4 signal averages, matrix 128 x 128, 1.72 x 1.72 x 5 mm voxel size, 12 tensor directions, iPAT 2, b value of 1000 sec/mm2 .

Contrast‐enhanced 3D FLASH: All 19 patients underwent whole brain 3D FLASH imaging in the sagittal plane after the administration of Magnevist. For this sequence, TR was 8.6 ms, TE 4.1 ms, 20 degree flip angle, 1 signal average, matrix 256 x 256; 1mm isotropic voxel size.

Contrast‐enhanced 3D FLAIR: All 17 patients who had repeat DTI sets also had 3D FLAIR sequences in the sagittal plane after the administration of Magnevist. For this sequence, the TR was 6000 ms, TE 353 ms, and TI 2200ms; 180 degree flip angle, 1 signal average, matrix 256 x 216; 1 mm isotropic voxel size. Note: before transmission to NCIA, all image sets with 1mm isotropic voxel size were “defaced” using MIPAV software or manually.

About the RIDER project The Reference Image Database to Evaluate Therapy Response (RIDER) is a targeted data collection used to generate an initial consensus on how to harmonize data collection and analysis for quantitative imaging methods applied to measure the response to drug or radiation therapy. The National Cancer Institute (NCI) has exercised a series of contracts with specific academic sites for collection of repeat "coffee break," longitudinal phantom, and patient data for a range of imaging modalities (currently computed tomography [CT] positron emission tomography [PET] CT, dynamic contrast-enhanced magnetic resonance imaging [DCE MRI], diffusion-weighted [DW] MRI) and organ sites (currently lung, breast, and neuro). The methods for data collection, analysis, and results are described in the new Combined RIDER White Paper Report (Sept 2008):

RIDER White Paper: Combined contracts report ( Sept 2008) PDF The long term goal is to provide a resource to permit harmonized methods for data collection and analysis across different commercial imaging platforms to support multi-site clinical trials, using imaging as a biomarker for therapy response. Thus, the database should permit an objective comparison of methods for data collection and analysis as a national and international resource as described in the first RIDER white paper report (2006):

RIDER White Paper: Executive Summary PDF RIDER White Paper: Editorial in Nature.com

Data and Resources

Additional Info

Field Value
Last Updated December 3, 2019, 14:15 (CST)
Created October 15, 2018, 20:51 (CST)

推薦資料集:


  • 政府資訊閱覽抄錄複製收費標準

    Payment instrument Free
    Update frequency Irregular
    政府資訊閱覽抄錄複製收費標準
  • 澎湖縣合法一般旅館、飯店名冊(統計至107年7月31日)-法文版

    Payment instrument Free
    Update frequency Irregular
    資料包含旅館名稱、電話、地址、座標、房間數及價格等資訊
  • 貿易調查委員會_98年3月特定產品之進口量價異常情形

    Payment instrument Free
    Update frequency Irregular
    因應我國加入WTO後,市場開放致進口產品對國內產業造成衝擊,經濟部貿易調查委員會自90年起委託台灣經濟研究院分階段建置貿易救濟預警系統。主要挑選歷年來較易發生傾銷案件的產業,並每月編製貿易調查預警速報(自99年12月起變更名稱為產業損害預警監測月報),自民國90年1月起至民國104年12月止共編製180期。相關訊息揭露於貿易調查委員會網站。...
  • 臺北市身心障礙人口數(73年至101年)

    Payment instrument Free
    Update frequency Irregular
    臺北市身心障礙人口數(73年至101年)時間數列統計資料
  • 110年現住人口統計表

    Payment instrument Free
    Update frequency Irregular
    本資料集提供110年現住人口統計資料