This is a collection of F-18 NaF positron emission tomography/computed tomography (PET/CT) images in patients with prostate cancer, with suspected or known bone involvement.
Imaging was performed on a Phillips Gemini TF PET/CT scanner based on 4x4x22mm LYSO (lutetium yttrium orthosilicate) crystal detection elements covering 18cm axial field of view (FOV) and 57cm imaging transaxial FOV. The time of flight resolution is 585ps. The scanner achieves a spatial resolution of 4.8mm at the center of the FOV. Data were reconstructed using the RAMLA iterative OSEM algorithm using 3 iterations and 33 subsets. The scanner uses CT based attenuation correction, along with randoms, normalization, dead time, and a model based scatter correction. The CT component of the scanner is a 16 slice helical CT. The CT images were generated using a low X-ray dose of 120KV, 60mAs setting.
The prescribed injected dose was 3mCi IV. Some of the patients had 2 baseline studies within 14 days of each other (with no intervening interventions). Many have follow-up PET/CT imaging performed following therapy (varied) at 6 +/-2months and 12 +/- 2 months. For scientific inquiries relating to this data set, please contact Drs. Karen Kurdziel (karen.kurdziel@nih.gov) or Liza Lindenberg (liza.lindenberg@mail.nih.gov).
