需同意授權

ISPY1

ACRIN 6657 was designed as a prospective study to test MRI for ability to predict response to treatment and risk-of-recurrence in patients with stage 2 or 3 breast cancer receiving neoadjuvant chemotherapy (NACT). ACRIN 6657 was conducted as a companion study to CALGB 150007, a correlative science study evaluating tissue-based biomarkers in the setting of neoadjuvant treatment of breast cancer. Collectively, CALGB 150007 and ACRIN 6657 formed the basis of the multicenter Investigation of Serial Studies to Predict Your Therapeutic Response with Imaging and moLecular Analysis (I-SPY TRIAL) breast cancer trial, a study of imaging and tissue-based biomarkers for predicting pathologic complete response (pCR) and recurrence-free survival (RFS).Participant Eligibility and Enrollment: Criteria for inclusion were patients enrolling on CALGB 150007 with T3 tumors measuring at least 3 cm in diameter by clinical exam or imaging and receiving neoadjuvant chemotherapy with an anthracycline-cyclophosphamide regimen alone or followed by a taxane. Pregnant patients and those with ferromagnetic prostheses were excluded from the study. The study was open to enrollment from May 2002 to March 2006. 237 patients were enrolled, of which 230 met eligibility criteria.

Acknowledgements This shared data set was provided by David Newitt, PhD and Nola Hylton, PhD from the Breast Imaging Research Program at UCSF, in collaboration with ACRIN, CALGB, the I-SPY TRIAL, and TCIA. Many thanks are due to The ACRIN 6657 trial team, The I-SPY 1 TRIAL team, and all the patients participating in these studies

Funding sources include NIH grants to UCSF (R01 CA132870 and U01 CA151235), ACRIN (UO1 CA079778 and UO1 CA080098), and CALGB (UO1 CA31964 and UO1 CA33601).

資料與資源

此資料集沒有資料

額外的資訊

欄位
最後更新 十二月 3, 2019, 14:29 (CST)
建立 二月 14, 2019, 10:19 (CST)

推薦資料集:


  • 新北市地政士業務檢查紀錄表-萬里區

    付費方式 免費
    更新頻率 不定期
    本市開業地政士進行業務檢查紀錄資料-萬里區
  • 無障礙廁所

    付費方式 免費
    更新頻率 不定期
    109年度花蓮縣社福相關資料
  • 高雄市幼兒園幼生數

    付費方式 免費
    更新頻率 不定期
    幼兒園幼生數
  • insight_test_17553

    付費方式 免費
    更新頻率 不定期
  • 臺北市政府政風處預防工作績效統計

    付費方式 免費
    更新頻率 不定期
    政風處預防工作績效統計,包括再防貪案件、業務稽核、預警作為、廉政倫理事件登錄、採購綜合分析、表揚獎勵廉能、政風法令宣導、受理公職人員財產申報、辦理財產申報資料實質審核、召開廉政透明委員會。